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Modular, Selection-Free Probiotic Platform for In Situ Delivery of Bacteriophage Endolysins in the Gut
BACKGROUND Clostridioides difficile infection (CDI) and its associated enteric disease caused by Clostridium perfringens, remain major drivers of morbidity, mortality, and healthcare expenditure. These pathogens persist due to antibiotic-mediated dysbiosis, high recurrence rates, and the limited durability of existing therapeutic options. In livestock...
Published: 5/5/2026
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Updated: 5/5/2026
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Inventor(s):
Joy Scaria
,
Amal Cheemadan
Keywords(s):
Category(s):
Technology Classifications > Animal Health
,
Technology Classifications > Biotech & Pharmaceutical
Megasphaera stantonii and Methods of Use
BACKGROUND The poultry industry is facing serious challenges due to necrotic enteritis (NE), a bacterial disease that causes severe damage to the intestines and results in billions of dollars in global losses each year. The situation has worsened since the phase-out of in-feed antibiotics, leaving producers with limited options for disease prevention....
Published: 3/30/2026
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Updated: 3/30/2026
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Inventor(s):
Guolong (Glenn) Zhang
,
Joy Scaria
Keywords(s):
Category(s):
Technology Classifications > Agriculture & Food Science