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Method and component of a novel antiviral targeting type 1 interferon response

BACKGROUND Influenza virus infection results in 200,000 hospitalizations, 36,000 deaths, and $87 billion in healthcare costs per year in the U.S. The current treatments, which consist of antiviral drugs that target viral proteins, only work if new strains of influenza virus do not emerge. However, influenza viral proteins readily mutate to create new,...

Published: 10/19/2022 | Inventor(s): Yujie Guo, Lin Liu

Keywords(s): Biotech & Pharmaceutical

Category(s): Technology Classifications > Biotech & Pharmaceutical

Engineering Mesenchymal Stem Cells for COPD Therapy

BACKGROUND The discovery of mesenchymal stem cells (MSCs) and induced pluripotent stem cells (iPSCs) have resulted in a plethora of opportunities to produce tissue-specific cell types for disease modeling, drug screening and treatments for diseases. For pulmonary diseases such as COPD, stem cells have been a proposed strategy to repair damaged lungs....

Published: 10/19/2022 | Inventor(s): Li Zhang, Lin Liu

Keywords(s): Biotech & Pharmaceutical

Category(s): Technology Classifications > Biotech & Pharmaceutical

Engineering Induced Pluripotent Stem Cells for COPD Therapy

Published: 10/19/2022 | Inventor(s): Li Zhang, Lin Liu

Keywords(s): Biotech & Pharmaceutical

Category(s): Technology Classifications > Biotech & Pharmaceutical

IncRNA FENDRR Exhibits Anti-fibrotic Activity in Pulmonary Fibrosis

BACKGROUND Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease characterized by a progressive decline in lung function that is chronic and fatal. The only treatment option shown to significantly extend life in a patient with IPF is a lung transplant, which only provides a ~40% survival rate 5 years post-operation. IPF usually occurs...

Published: 7/19/2023 | Inventor(s): Chaoqun Huang, Lin Liu

Keywords(s):

Category(s): Technology Classifications > Biotech & Pharmaceutical