Search Results - akhilesh+ramachandran

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Single Step Multiplexed Metagenome Sequencing based Bacterial/Viral Pathogen Detection for Bovine Respiratory Disease

BACKGROUND Traditional pathogen identification is a cornerstone of both veterinary and medical diagnostics. For decades, methods such as Polymerase Chain Reaction (PCR) and bacterial or culturing have been widely used. However, these techniques are often time-consuming and resource intensive. Typically, only a limited number of pathogens can be detected...

Published: 9/19/2025 | Inventor(s): Jerry Malayer, Sai Narayanan, Kitty Cardwell, Andres Espindola Camacho, Akhilesh Ramachandran

Keywords(s):

Category(s): Technology Classifications > Agriculture & Food Science, Technology Classifications > Animal Health, Technology Classifications > Chemistry, Technology Classifications > Engineering, Technology Classifications > Biotech & Pharmaceutical

Single Step, Multiplexed, Metagenome Sequencing based Bacterial Pathogen Detection for Gastrointestinal Disturbances (Salmonella spp., C. perfringens, E. coli, Klebsiella spp.)

BACKGROUND Gastrointestinal disturbances can be caused by a wide range of pathogens or an overabundance of certain microbial families. Detecting pathogenic bacteria and analyzing the overall microbial composition of the gut can help identify imbalances that may lead to dysbiosis. Current diagnostic technologies often struggle to detect more than a...

Published: 8/29/2025 | Inventor(s): Jerry Malayer, Sai Narayanan, Andres Espindola Camacho, Kitty Cardwell, Akhilesh Ramachandran

Keywords(s):

Category(s): Technology Classifications > Animal Health, Technology Classifications > Agriculture & Food Science, Technology Classifications > Software

Single Step Metagenome Sequencing based Detection of SARS-CoV-2

BACKGROUND Traditional detection of SARS-CoV-2 has primarily relied on real time Reverse Transcription Polymerase Chain Reactions (RT-PCR), a highly sensitive and specific method for identifying viral RNA. This technique is typically conducted in laboratory environments and can require several days to obtain results. Given the rapid transmission of...

Published: 8/22/2025 | Inventor(s): Jerry Malayer, Sai Narayanan, Kitty Cardwell, Andres Espindola Camacho, Akhilesh Ramachandran

Keywords(s):

Category(s): Technology Classifications > Biotech & Pharmaceutical

Nucleic acid sequence-based detection and characterization using genome-level pseudo-imaging and machine learning

BACKGROUND Whole genome sequencing provides a complete snapshot of an organism’s genetic code, enabling evolutionary inference through quantification of nucleotide similarities. However, reference databases exhibit bias toward well-studied species due to long-tail distributions and sampling gaps. These imbalances risk species misidentification...

Published: 7/25/2025 | Inventor(s): Akhilesh Ramachandran, Vishalini Laguduva, Sathyanarayan (Sathya) Aakur

Keywords(s):

Category(s): Technology Classifications > Animal Health, Technology Classifications > Research Tools, Technology Classifications > Medical Device & Diagnostic