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Single Step Multiplexed Metagenome Sequencing based Bacterial/Viral Pathogen Detection for Bovine Respiratory Disease

BACKGROUND Traditional pathogen identification is a cornerstone of both veterinary and medical diagnostics. For decades, methods such as Polymerase Chain Reaction (PCR) and bacterial or culturing have been widely used. However, these techniques are often time-consuming and resource intensive. Typically, only a limited number of pathogens can be detected...

Published: 9/19/2025 | Inventor(s): Jerry Malayer, Sai Narayanan, Kitty Cardwell, Andres Espindola Camacho, Akhilesh Ramachandran

Keywords(s):

Category(s): Technology Classifications > Agriculture & Food Science, Technology Classifications > Animal Health, Technology Classifications > Chemistry, Technology Classifications > Engineering, Technology Classifications > Biotech & Pharmaceutical

Single Step, Multiplexed, Metagenome Sequencing based Bacterial Pathogen Detection for Gastrointestinal Disturbances (Salmonella spp., C. perfringens, E. coli, Klebsiella spp.)

BACKGROUND Gastrointestinal disturbances can be caused by a wide range of pathogens or an overabundance of certain microbial families. Detecting pathogenic bacteria and analyzing the overall microbial composition of the gut can help identify imbalances that may lead to dysbiosis. Current diagnostic technologies often struggle to detect more than a...

Published: 8/29/2025 | Inventor(s): Jerry Malayer, Sai Narayanan, Andres Espindola Camacho, Kitty Cardwell, Akhilesh Ramachandran

Keywords(s):

Category(s): Technology Classifications > Animal Health, Technology Classifications > Agriculture & Food Science, Technology Classifications > Software

Single Step Metagenome Sequencing based Detection of SARS-CoV-2

BACKGROUND Traditional detection of SARS-CoV-2 has primarily relied on real time Reverse Transcription Polymerase Chain Reactions (RT-PCR), a highly sensitive and specific method for identifying viral RNA. This technique is typically conducted in laboratory environments and can require several days to obtain results. Given the rapid transmission of...

Published: 8/22/2025 | Inventor(s): Jerry Malayer, Sai Narayanan, Kitty Cardwell, Andres Espindola Camacho, Akhilesh Ramachandran

Keywords(s):

Category(s): Technology Classifications > Biotech & Pharmaceutical

Sonosensitized Cancer Immunotherapy with Nanoparticles

BACKGROUND The ability of the immune system to recognize, attack, and eliminate tumors is well established. However, several tumor types (such as, but not limited to, melanoma, pancreatic, and breast tumor types) manifest a variety of immunosuppressive mechanisms to evade immune attack. As such, reversing the protective immune suppression mechanisms...

Published: 7/19/2023 | Inventor(s): Sri Sethuraman, Jerry Malayer, Mohit Singh, Ashish Ranjan

Keywords(s): Biotech & Pharmaceutical

Category(s): Technology Classifications > Biotech & Pharmaceutical