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Targeted Delivery of Personal Sprays
BACKGROUND Electrostatic spray guns are currently being used only in paint applications, using voltage to directly deliver the aerosol to the target area due to traditional atomization devices causing loss of product to the surrounding environment. This loss of product is also the case with personal spray products like perfumes, deodorants, and hair...
Published: 9/19/2025   |   Inventor(s): Khaled Sallam
Keywords(s):  
Category(s): Technology Classifications > Medical Device & Diagnostic, Technology Classifications > Recreational, Technology Classifications > Engineering, Technology Classifications > Chemistry, Technology Classifications > Animal Health, Technology Classifications > Biotech & Pharmaceutical
Single Step Multiplexed Metagenome Sequencing based Bacterial/Viral Pathogen Detection for Bovine Respiratory Disease
BACKGROUND Traditional pathogen identification is a cornerstone of both veterinary and medical diagnostics. For decades, methods such as Polymerase Chain Reaction (PCR) and bacterial or culturing have been widely used. However, these techniques are often time-consuming and resource intensive. Typically, only a limited number of pathogens can be detected...
Published: 9/19/2025   |   Inventor(s): Jerry Malayer, Sai Narayanan, Kitty Cardwell, Andres Espindola Camacho, Akhilesh Ramachandran
Keywords(s):  
Category(s): Technology Classifications > Agriculture & Food Science, Technology Classifications > Animal Health, Technology Classifications > Chemistry, Technology Classifications > Engineering, Technology Classifications > Biotech & Pharmaceutical
Photocatalytic activity of Cu2O-Pd NPs for Carbon-Carbon (C-C) Coupling Reactions under Visible Light Illumination
BACKGROUND There is an increasing need for sourcing thermal energy and sustainable catalytic processes at low cost and with minimal carbon emissions, especially within the bulk and fine chemical industries. These sectors rely heavily on carbon-carbon (C-C) bond-forming reactions to synthesize valuable chemicals, pharmaceuticals, and materials. However,...
Published: 8/22/2025   |   Inventor(s): Marimuthu (Mari) Andiappan, Ravi Teja Addanki Tirumala
Keywords(s):  
Category(s): Technology Classifications > Biotech & Pharmaceutical, Technology Classifications > Engineering > Chemical Engr, Technology Classifications > Chemistry, Technology Classifications > Environment & Energy
Single Step Metagenome Sequencing based Detection of SARS-CoV-2
BACKGROUND Traditional detection of SARS-CoV-2 has primarily relied on real time Reverse Transcription Polymerase Chain Reactions (RT-PCR), a highly sensitive and specific method for identifying viral RNA. This technique is typically conducted in laboratory environments and can require several days to obtain results. Given the rapid transmission of...
Published: 8/22/2025   |   Inventor(s): Jerry Malayer, Sai Narayanan, Kitty Cardwell, Andres Espindola Camacho, Akhilesh Ramachandran
Keywords(s):  
Category(s): Technology Classifications > Biotech & Pharmaceutical
Point-of-Need Colorimetric Serum and Salivary Insulin Immunosensor
BACKGROUND Diabetes is a chronic disease characterized by impaired insulin production or action, resulting in poor regulation of glucose. While current continuous glucose monitoring (CGM) technologies are vital tools for diabetes management, they primarily measure glucose, which exists at high (millimolar) concentrations. However, insulin, the hormone...
Published: 8/14/2025   |   Inventor(s): Sadagopan Krishnan
Keywords(s):  
Category(s): Technology Classifications > Biotech & Pharmaceutical, Technology Classifications > Animal Health
Discovery of ammonium salts of alpha-fluoroarylated Meldrum's acid derivatives
BACKGROUND Meldrum’s acid is widely used as a building block in the synthesis of diverse organic compounds, including natural products and pharmaceuticals. Despite its broad utility, efficient and general methods for the direct mono-arylation of Meldrum’s acid remain limited. At the same time, there is a growing demand for partially fluorinated...
Published: 8/11/2025   |   Inventor(s): Sameera Senaweera, Jimmie Weaver
Keywords(s): Research Tools & Methods
Category(s): Technology Classifications > Biotech & Pharmaceutical
Protein engineering and protein optimization based on ancestral sequence reconstruction using evolutionary molecular meandering and fitness well dragging
BACKGROUND An Ancestral Sequence Reconstruction (ASR) highlights the evolutionary pathway of proteins and how some protein homologs have differed in both structural and functional composition throughout evolution. These differing compositions have resulted in proteins with variable abilities, which may have previously been overlooked due to the lack...
Published: 6/27/2025   |   Inventor(s): Wouter Hoff, Rosalie Dohmen
Keywords(s):  
Category(s): Technology Classifications > Biotech & Pharmaceutical, Technology Classifications > Agriculture & Food Science
PulmoPrecise: Artificial Intelligence (AI) Empowered User-Centered Smart Inhaler for Targeted Drug Delivery to Designated Lung Sites
Background Managing pulmonary diseases such as asthma, chronic obstructive pulmonary disease, and cystic fibrosis presents considerable challenges, particularly in achieving directed drug delivery to the lungs at the necessary doses. The primary approach for both long-term treatment and rescue drug delivery involves the use of inhaler devices, wherein...
Published: 3/26/2025   |   Inventor(s): Yu Feng
Keywords(s):  
Category(s): Technology Classifications > Biotech & Pharmaceutical, Technology Classifications > Software
A novel class of antibiotics against non-tuberculous mycobacterial infection
BACKGROUND Nontuberculous mycobacteria (NTM) infections are becoming an increasing public health concern, particularly for individuals with chronic lung conditions, those who are immunosuppressed, or people exposed to contaminated water sources. Unlike tuberculosis, which is caused by Mycobacterium tuberculosis, NTM includes over 190 species, many...
Published: 2/7/2025   |   Inventor(s): Yong Cheng, Xuejuan Tan, Audrey Dagnell
Keywords(s):  
Category(s): Technology Classifications > Animal Health, Technology Classifications > Biotech & Pharmaceutical
Lifespan Prolonging Probiotic
­BACKGROUND Probiotics, which are live microorganisms known to promote gut health, have attracted significant attention for their ability to positively impact the gut microbiome. By improving digestion, nutrient absorption, and immune function, these beneficial bacteria contribute to overall health. Recent studies have also suggested that probiotics...
Published: 10/31/2024   |   Inventor(s): Jacob Manjarrez, Ratnakar Deole
Keywords(s):  
Category(s): Technology Classifications > Biotech & Pharmaceutical
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